研究計畫

國科會計畫 (主持人)

• 應用光固化3D生物列印技術製作微生物固定化顆粒並用於處理環境荷爾蒙類界面活性劑 (2025/08-2026/07)

• 開發胞外聚合物固定化新技術加速環境荷爾蒙類新興污染物之生物分解-以辛基苯酚聚氧乙烯醇 (octylphenol polyethoxylates) 為例 (2023/08-2025/07)

• 土壤污染整治列車之新技術－併同紫外光照射、光催化反應與生物分解加速處理土壤/水系統中之持久性及新興污染物 (2022/08-2023/07)

• 廚餘堆肥高值化技術-開發高抗菌胜肽之環境生物製劑 (2021/11-2022/10)

• 應用抗UV微生物結合奈米光觸媒包埋顆粒處理土壤/水系統中之新興污染物-以十溴聯苯醚為例 (2021/08-2022/07)

• SBR系統在不同操作條件下處理新興污染物-二苯甲酮防曬劑及其微生物多樣性 (2019/08~2021/07)

• 利用天然抗菌材料包覆奈米氧化鋅並應用於處理台灣傳統市場生物氣膠 (2017/08-2019/07)

• 利用生物淋溶法提高底泥難分解有機污染物之生物復育-以多苯環化合物為例 (2015/08-2017/07)

• 結合生物分解及LED UV光降解多溴聯苯醚污染土壤之綠色整治 (2013/08-2015/07)

• 土壤中環境荷爾蒙類界面活性劑之生物復育-以辛基苯酚為例 (2010/08-2012/07)

• 應用生物釋酸泥漿反應器處理受高環數PAH污染之酸性土壤及其功能性基因鑑定 (2009/08-2010/07)

• 整合生物分解與Fenton法處理受高環數PAH污染之土壤 (2008/08-2010/07)

• 研發高效率處理生物氣膠之奈米光觸媒空氣清淨機 (2007/11-2008/10) 

國科會(科技部)計畫 (共同主持人)

• 微生物技術應用於文蛤養殖環境之監測與優化 (1/3)  (2017/07-2018/06)
• 綠色海水養殖環境微生物製劑之開發與應用-綠色海水養殖環境微生物製劑之開發與應用 (2015/08-2018/07)
• 以游離及固定化酵素促進難分解有機污染物與天然土壤有機質滲合/偶聯反應之研究 (2012/08-2015/07) 
• 醫療用藥物污染環境之復育研究 (2011/08-2014/07)
• 溴化阻燃劑污染之河川底泥與陸棲環境之復育研究-總計畫及子計畫一 (2008/08-2011/07)
• 湖泊中微囊藻毒之化學傳輸行為與生物分解研究 (2008/08-2011/07)

其他政府機構及產學合作計畫 (主持人)

• 應用生物固定化顆粒加速受柴油汙染土壤之生物復育, 環境部 環境管理署 土污基金會 (2024/11-2025/10)
• 永續城鄉的推廣與應用-東吳大學與北埔鄉對地方創生的合作與實踐, 教育部 大學社會責任(USR) 計畫 (2023/01-2023/12)
• 應用底泥微生物同時去除地下水重金屬並生產奈米金屬, 環保署 土污基金會 (2022/09-2023/08)
• 污水處理微生物辨識與諮詢, 財團法人中興工程顧問社 (2022/10-2023/05)
• 不同環境條件離子液體抑菌能力分析, 金益世股份有限公司 (2021/04- 2021/10)
• 高效中溫發酵廚餘堆肥之微生物菌群分析, 金益世股份有限公司 (2021/03-2021/08)
• 污水處理場活性污泥微生物辨認與諮詢, 財團法人中興工程顧問社 (2020/05-2021/04)
• 堆肥微生物菌相及菌數分析, 金益世股份有限公司 (2020/07-2020/10)
• 有機堆肥分解受十溴二苯醚污染底泥及其生物多樣性, 環保署土污基金會 (2012/12-2013/12)
• 廢棄藥品於水體環境之毒性及其風險評估, 行政院衛生署/中華民國藥師公會全國聯合會 (2011/01-2011/11)   

代表著作 (Featured papers) 【* = Corresponding author】

1. Chang, Y.-T., Chen, I.-C. Lau, S.H., Liu, W.-T., Chiang, C.-C. (2025/06) Characterizing risk through particle size analysis of airborne bacteria and fungi in a wholesale traditional fish market, Indoor Air 2025, 6572652. http://10.1155/ina/6572652 (SCI, 2024 IF=4.3)
2. Lau, S.H., Chang, Y.-T.* (2024/08) Selective biodegradation of octylphenol polyethoxylates with different ethoxylate length chains by aerobic bacterial culture, Chemosphere 361, 142538. https://doi.org/10.1016/j.chemosphere.2024.142538 (EI)
4. Lau, S.H., Su, C.-L., Yu, T.-Y., Zhong, Y., Xu, X., Jane W.-N., Chang, Y.-T. * (2023/09) The use of immobilised bacteria cross-linked within magnetic alginate beads enhances the treatment of benzophenone-type UV filter chemicals by the SBR system, Chemosphere 334, 139038. http://doi.org/10.1016/j.chemosphere.2023.139038 (EI).
5. Chang, Y.-T., Liu, W.-T., Chen, I.-C., Chiang, C.-C., Lau, S.H. (2023/08). The indoor concentration and size distribution of airborne bacteria in a typical traditional market, Aerosol and Air Quality Research 23, 220402. https://doi.org/10.4209/aaqr.220402 (SCI, 2023 IF=2.5).
6. Su, C.-L., Lau, S.H., Yeh, H.-Y., Chang, Y.-T.* (2023/02) Biological treatment of benzophenone-type UV filter wastewater in a sequencing batch reactor (SBR), International Biodeterioration & Biodegradation 177, 105534. https://doi.org/10.1016/j.ibiod.2022.105534 (SCI, 2023 IF=4.1).
7. Lau, S.H., Lin, I.-C., Su, C.-L., Chang, Y.-T.*, Jane, W.-N. (2022/11) Synthesis of cross-linked magnetic chitosan beads containing immobilised bacteria for use in the aerobic biodegradation of benzophenone type UV filter chemicals, Chemosphere 307, Part 3, 136010. https://doi.org/10.1016/J.CHEMOSPHERE.2022.136010 (SCI, 2022 IF=8.8).
8. Lau, S.H., Hung C.-H., Chang Y.-T.* (2022/03) Bacterial community and physiological characteristics of octylphenol polyethoxylate biodegradation in soil slurries, Applied Soil Ecology 171, https://doi.org/10.1016/j.apsoil.2021.104317 (SCI, 2022 IF=4.8).
9. Hsu, J.-S., Yu, T.-Y., Wei, D.-J., Jane, W.-N., Chang, Y.-T.* (2022/02) Degradation of decabromodiphenyl ethers in an aerobic clay slurry microcosm using a novel immobilization technique, Microorganisms 10(2), 402. https://doi.org/10.3390/microorganisms10020402 (SCI, 2022 IF=4.5).
10. Wei, D.-J., Liu, W.-D., Chin, H.-T., Lin, C.-H., Chen, I.-C., Chang, Y.-T. (2021/04) An investigation of airborne bioaerosols and endotoxins present in indoor traditional wet markets before and after operation in Taiwan: A Case Study, International Journal of Environmental Research and Public Health 18(6), 2945.  https://doi.org/10.3390/ijerph18062945 (SCI, 2021 IF=4.614).
11. Chang, Y.-T., Chen, H.-C., Chou, H.-L., Li, H., Boyd, S.A. (2021/02) A coupled UV photolysis-biodegradation process for the treatment of decabrominated diphenyl in an aerobic novel bioslurry reactor, Environmental Science and Pollution Research, 28, pp.6078-6089. doi:10.1007/s11356-020-10753-9 (SCI, 2021 IF=5.190).
12. Chang, Y.-T., Chao, W.-L., Chen, H.-Y., Li, H., Boyd S.A. (2020/04) Characterization of a sequential UV photolysis-biodegradation process for treatment of decabrominated diphenyl ethers in sorbent/water systems, Microorganisms, 8(5), pp. 633. doi:10.3390/microorganisms8050633 (SCI, 2020 IF=4.128).
13. Ying, C.*, Chang, M.-J., Chang, Y.-T., Chao, W.L., Yen, S.-L., Hsu J.-T. (2020/03) Photosynthetic bacteria enhanced water quality and integrity of microbial community composition of integrated multitrophic aquaculture system of milkfish Chanos chanos coastal farming, Fisheries Science, 86, 329–338. doi:10.1007/s12562-019-01387-z (SCI, 2019 IF=1.173).
14. Chang, Y.-T. , Chou, H.-L., Li, H., Boyd, S.A. (2019/06) Variation of microbial communities in aquatic sediments under long-term exposure to decabromodiphenyl ether and UVA irradiation, Sustainability, 11(14), pp. 3773. doi:10.3390/su11143773 (SCI, 2019 IF=2.576).
15. Yu, C.C., Chang, T.-C., Liao, C.S, Chang, Y-T * (2019/01) Comparative microbial community and functional genes of free-living and soil-attached bacteria in aerobic slurry reactor treating high-molecular-weight PAH, Sustainability 11(7), pp.1088. doi: 10.3390/su11041088 (SCI, 2019 IF=2.576).
16. Chang, T.-J., Chang, Y.-H., Chao, W.-L., Jane, W.-N., Chang, Y.-T.* (2018/12) Effect of hydraulic retention time on electricity generation using a solid plain-graphite plate microbial-fuel-cell anoxic/oxic process for treating pharmaceutical sewage, Journal of Environmental Science and Health, Part A, 53, pp. 1185-1897. doi: 10.1080/10934529.2018.1530338 (SCI, 2018 IF=1.536).
17. Hsiung, Y. Y., Chang, M.-J., Chang, Y.-T., Yeh, S.-L., Chang, S.-J., Ying, C., Chao, W.-L. (2018/08) Photosynthetic purple sulfur bacterium Marichromatium purpuratum RuA2 induces changes in water quality parameters, the occurrence of sulfonamide resistance gene and microbial community structure of marine aquaculture, Aquaculture 493, pp. 68-78. doi:10.1016/j.aquaculture.2018.04.055 (SCI, 2017 IF=2.710).
18. Ying, C.*, Chang, M.-J., Hu, C.-H., Chang, Y.-T., Chao, W.-L., Yeh, S.-L., Chang, S.-J., Hsu, J.-T. (2018/12) The effects of marine farm-scale sequentially integrated multi-trophic aquaculture systems on microbial community composition, Prevalence of sulfonamide-resistant bacteria and sulphonamide resistance gene sul1, Science of Total Environment, 643, pp. 681-691. doi: 10.1016/j.scitotenv.2018.06.204 (SCI, 2017 IF=4.610).
19. Tsao, S., Wei, D.-J., Chang, Y.-T., Lee, J.-F. (2017/10) Aerobic biodegradation of Microcystin-LR by an indigenous bacterial mixed culture isolated in Taiwan, International Biodeterioration & Biodegradation, 124, pp. 101-108. doi:10.1016/j.ibiod.2017.04.011 (SCI, 2017 IF=3.562).
20. Chang, Y.T.*, Lo, T., Chou, H.-L, Laio, Y.-F., Lin, C. C., Chen, H.-T. (2016/09) Anaerobic biodegradation of BDE-209-contaminated sediment by organic composts, International Biodeterioration & Biodegradation, 113, pp. 228-237. doi:10.1016/j.ibiod.2016.04.017 (SCI, 2017 IF=3.562).
21. Chou, H.-L., Hwa, M.-Y., Lee, Y.-C., Chang, Y.-J., Chang, Y.-T.* (2016/03) Microbial degradation of decabromodiphenyl ether (DBDE) in soil slurry microcosms, Environmental Science and Pollution Research, 23(6), pp. 5255-5267. doi: 10.1007/s11356-015-5767-x (SCI, 2017 IF=2.800).
22. Chang, Y.-T., Lee, J.-F., Liu, K.-H., Liao, Y.-F., Yang, V. (2016/03) Immobilization of fungal laccase onto the surfactant-modified clay: application for PAH degradation, Environmental Science and Pollution Research 23(5), pp. 4024-4035. doi:10.1007/s11356-015-4248-6 (SCI, 2017 IF=2.800).
23. Chang, Y.-J.*, Hung, C.-H., Lee, J.-W., Chang, Y.-T., Lin, F.-Y., Chuang C.-J. (2015/08) A study of microbial population dynamics associated with corrosion rates influenced by corrosion control materials, International Biodeterioration & Biodegradation 102, pp. 330-338. doi:10.1016/j.ibiod.2015.03.008 (SCI, 2017 IF=3.562).
24. Chang, Y.-T.*, Chou, H.-L., Chao, H.-P., Chang, Y.-J. (2015/08) The influence of sorption on polyaromtic hydrocarbon biodegradation in the presence of modified nonionic surfactant organoclays, International Biodeterioration & Biodegradation 102, pp. 237-244. doi: 10.1016/j.ibiod.2015.03.004 (SCI, 2017 IF=3.562).
25. Chang, Y.-T.*, Hung C.-H., Chou, H.-L. (2014/12) Effect of the polyethoxylate laurylether addition on phenanthrene biodegradation in the soil/water systems, Journal of Environmental Science and Health, Part A, 49(14), pp. 1672-1684. doi: 10.1080/10934529.2014.951228 (SCI, 2017 IF=1.561).
26. Chang, Y.-T. *, Yang, C.-W., Chang, Y.-J., Chang, T.-C., Wei, D.-J. (2014) The treatment of PPCP-containing sewage in an anoxic/aerobic reactor coupled with a novel design of solid plain graphite-plates microbial fuel cell, BioMed Research International, Special issue: Renewable Energy and Alternative Fuel Technologies, 2014, Article ID 765652. doi:10.1155/2014/765652 (SCI, 2017 IF=2.583).
27. Chang, Y.-J.*, Chang, Y.-T., Hung, C.-H., Lee, J.-W., Liao, H.-M., Chou H.-L. (2014/11) Microbial community analysis of anaerobic bio-corrosion in different ORP profiles, International Biodeterioration & Biodegradation 95, pp 93-101. doi:10.1016/j.ibiod.2014.04.008 (SCI, 2017 IF=3.562).
28. Chang, Y.-T.*, Chang Y.-J. (2014/01), The investigation of bacterial indicators and point source pollution in the Nanshi River, Taiwan: a case study, Desalination and Water Treatment 52(4-6), pp 1130-1142. doi:10.1080/19443994.2013.826402 (SCI, 2017 IF=1.383).
29. Chou, S.-L., Chang, Y.-T.*, Liao, Y.-F., Lin, C.-H. (2013/11) Biodegradation of decabromodiphenyl ether (BDE-209) by bacterial mixed cultures in the soil/water system, International Biodeterioration & Biodegradation 85, pp 671-682. doi:10.1016/j.ibiod.2013.05.006 (SCI, 2017 IF=3.562).
30. Bai M.-Y., Chang, Y.-T., Tasi, J.-C., Wei, D.-J. (2013/01) Tea tree oil-containing chitosan/polycaprolactone electrospun nonwoven mats: A systematic study of the anti-bacterial properties In Vitro, International Journal of Nanotechnology Vol. 10 (10/11), pp 959-972. doi:10.1504/IJNT.2013.058122 (SCI, 2017 IF=0.512).
31. Chang, Y.-T.*, Chang, Y.-J. , Chiang C.-C. (2012), Synthesis of magnetic photocatalystic particles for bacterial control, Applied Mechanics and Materials Vol. 217-219, pp 821-825.  doi:10.4028/www.scientific.net/AMM.217-219.821 (EI).
32. Chang, Y.-T.*, Lin, C.-H., Chang, Y.-J., Chiang, C.-C. (2012), Bactericidal activity of photocatalytic reaction in aqueous media by the TiO2-coated stainless steel sieves, Advanced Materials Research Vol. 347-353, pp 1906-1910.  doi:10.4028/www.scientific.net/AMR.347-353.1906 (EI).
33. Hung, C.-H.*, Chang, Y.-T., Chang, Y.-J. (2011/09), Roles of microorganisms other than Clostridium and Enterobacter in anaerobic fermentative biohydrogen production systems - A review, Bioresource Technology, 102(18), pp 8437-8444. doi:10.1016/j.biortech.2011.02.084 (SCI, 2014 IF=4.494).
34. Chang, Y.-T., Thirumavalavan, M., Lee, J.-F*. (2010/02), Effects of PAH biodegradation in the presence of non-ionic surfactants on a bacterial community and its exoenzymatic activity, Journal of Environmental Science and Health, Part A, 45(4), pp 421-431. doi:10.1080/10934520903540141 (SCI, 2013 IF=1.135).
35. Chang, Y.-J.*, Chang, Y.-T. , Hung, C.-H. (2008/11), The use of magnesium peroxide in restraining sulfate-reducing bacteria under anoxic condition, Journal of Industrial Microbiology and Biotechnology, 35(11), pp 1481-1491. doi:10.1007/s10295-008-0450-6. (SCI, 2013 IF=2.505).
36. Chang, Y.-T.*, Chang, M.-C., Kang, H.-Y. (2008/10), Enhance Fenton-biological treatment for PAH-contaminated soil by acidophilic bacteria (Abstract), Journal of Biotechnology, 136S, pp S692. doi:10.1016/j.jbiotec.2008.07.1606 (SCI, 2013 IF=2.884).
37. Chang, Y.-T.*, Lee, J.-F., Chao H.-P. (2008/10), The sorptive influence of nonionic surfactant on PAH biodegradation in soil/water systems (Abstract) , Journal of Biotechnology, 136S, pp S691-692. doi:10.1016/j.jbiotec.2008.07.1605 (SCI, 2013 IF=2.884).
38. Chao, H.-P., Chang, Y.-T., Lee, J.-F.*, Lee, C.-K., Chen, I.-C. (2008/03), Selective adsorption and partitioning of nonionic surfactants onto solids via liquid chromatography mass spectra analysis, Journal of Hazardous Materials 152(1), pp 330-336. (SCI, 2013 IF=4.331).
39. Chang, Y.-T., Lee, J.-F.*, Chao, H.-P. (2007), Variability of communities and physiological characteristics between free-living bacteria and attached-bacteria during the PAH biodegradation in soil/water system, European Journal of Soil Biology, 43, pp 283-296. (SCI, 2013 IF=2.146).
40. Chang, Y.-T., Lee, J.-F.*, Hung, C.-H. (2007), PAH biodegradation in surfactant-water systems based on the theory of cohesive energy density (CED), Journal of Chemical Technology and Biotechnology, 82(5), pp 442-452. (SCI, 2013 IF=2.494).
41. Chang Y.-J.*, Chang, Y.-T., Chen, H.-J. (2007), A method for controlling hydrogen sulfide in water by adding solid phase oxygen, Bioresource Technology, 98(2) pp 478-483. (SCI, 2013 IF=5.039).
42. Lee, J.-F.*, Chang, Y.-T., Chao, H.-P., Huang, H.-C., Hsu, M.-H. (2006), Organic compound distribution between nonionic surfactant solution and natural solids: applicability of a solution property parameter, Journal of Hazardous Materials, 129, pp 282-289. (SCI, 2013 IF=4.331).
43. Chang, Y.-T.; Lee, J. -F.*, Chao, H.-P., Liao, W.-L. (2006), Bacterial community changes with N’- N’ dimethylforamide (DMF) additive during polycyclic aromatic hydrocarbons (PAH) Biodegradation, Environmental Technology, 27(1), pp 1-14. (SCI, 2016 IF=1.751).
44. Chang, Y.-J.*, Chang, Y.-T., Huang, H.-K., Chen, W.-F. (2004), Stagnant Water Variation in Observation Wells in Taiwan-Site Survey and Purging Investigation, Journal of the Chinese Institute of Environmental Engineering (Sustainable Environment Research), 14(1), pp 25-32.